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The inferior vena cava is a large vein that carries the deoxygenated from the lower and middle body into the of the . It is formed by the joining of the right and the left common iliac veins, usually at the level of the fifth .

The inferior vena cava is the lower ("inferior") of the two , the two large that carry deoxygenated from the body to the right atrium of the heart: the inferior vena cava carries blood from the lower half of the body whilst the superior vena cava carries blood from the upper half of the body. Together, the venae cavae (in addition to the , which carries blood from the muscle of the heart itself) form the venous counterparts of the .

It is a large vein that lies posterior to the and runs along the right side of the . It enters the right auricle at the lower right, back side of the heart. The name derives from .


Structure
The IVC is formed by the joining of the left and right common iliac veins and brings collected blood into the of the heart. It also with the (which runs on the right side of the vertebral column) and venous next to the .

The inferior vena cava begins as the left and right common iliac veins behind the unite, at about the level of . It passes through the thoracic diaphragm at the at the level of T8. It passes to the right of the .


Tributaries
The specific levels of the tributaries are as follows:

[[hepatic veins]], inferior phrenic vein
right [[suprarenal vein]], [[renal veins]]
right [[gonadal vein]]
[[lumbar veins]]
common iliac veins

Because the inferior vena cava is located to the right of the midline, drainage of the tributaries is not always symmetrical. On the right, the and drain into the inferior vena cava directly. On the left, they drain into the which in turn drains into the inferior vena cava. By contrast, all the and usually drain directly into the inferior vena cava.


Development
In the , the inferior vena cava and right auricle are separated by the valve of the inferior vena cava, also known as the Eustachian valve. In the adult, this valve typically has totally regressed or remains as a small fold of .


Anatomy variations
The anatomy of the IVC can exhibit abnormalities in approximately 8.7% of the global population. These variations may arise during its development, specifically between the 4th and 8th weeks of gestation, due to the intricate process of vessel formation. The IVC is composed of four segments formed from the anastomoses of various vessels: hepatic, suprarenal, renal, and infrarenal. The hepatic segment originates from the vitelline vein, while the suprarenal segment includes a portion of the right subcardinal vein that does not regress. The renal segment is created through the anastomoses of the right suprasubcardinal and postsubcardinal veins, and the infrarenal segment derives from the right supracardinal vein. The subcardinal and supracardinal veins gradually replace the postcardinal veins, which persist as the common iliac veins within the pelvis.

The formation of the IVC is a complex process that can result in anomalies. These anomalies are more frequently observed in individuals with other cardiovascular defects. The most common variants are the duplicated IVC and left IVC. In a duplicated IVC, both supracardinal veins persist, a rare variant affecting 0.2–3% of the population. Most of these anatomical variations are asymptomatic, but their identification is crucial for the accurate planning of complex surgeries to avoid complications. Ultrasound (US) systems are typically used to identify these variations; however, other techniques such as computed tomography (CT), which involves ionizing radiation, or magnetic resonance imaging (MRI), which is more costly, are often preferred due to the user-dependent nature of US analysis.

In between 0.2% to 0.3% of people, the inferior vena cava may be duplicated beneath the level of the renal veins.


Function
The inferior vena cava is a . It carries deoxygenated blood from the lower half of the body to the of the .
(2025). 9780808923718, Churchill Livingstone.

The corresponding vein that carries deoxygenated blood from the upper half of the body is the superior vena cava.


Diameter evaluation of IVC
Various image-processing methods have been applied to US scans of the IVC. The number of algorithms is slightly larger for the analysis of transverse than longitudinal view. This may stem from the fact that it is easier to segment a closed cross-section than an open long-axis portion of the IVC, as the latter requires careful tracking of the region of interest. In recent years, deep learning approaches are gaining more importance, so that further developments are expected in the future in such a direction.


Clinical significance
Health problems attributed to the IVC are most often associated with it being compressed (ruptures are rare because it has a low intraluminal ). Typical sources of external pressure are an enlarged (abdominal aortic aneurysm), the (aortocaval compression syndrome) and abdominal malignancies, such as colorectal cancer, renal cell carcinoma and . Since the inferior vena cava is primarily a right-sided structure, unconscious pregnant women should be turned on to their left side (the recovery position), to relieve pressure on it and facilitate venous return. In rare cases, straining associated with can lead to restricted blood flow through the IVC and result in (fainting).

Blockage of the inferior vena cava is rare and is treated urgently as a life-threatening condition. It is associated with deep vein thrombosis, , liver transplantation and surgical procedures such as the insertion of a in the in the .Geehan DM, Inferior Vena Caval Thrombosis, emedicine.com, URL: http://www.emedicine.com/med/topic2718.htm, Accessed: August 3, 2005. Trauma to the vena cava is usually fatal as unstoppable occurs.

==Additional images==


See also


External links
  • - "Posterior Abdominal Wall: Tributaries to the Inferior Vena Cava"

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